Sustalad 250 mg/ml (Sustanon) 10ml Vials

• Active ingredients: Testosterone isocaproate 60 mg, testosterone phenylpropionate 60 mg, testosterone propionate 30 mg, testosterone decanoate 100 mg
• Type: Anabolic steroid (Testosterone derivative)
• Form: Injections

Description

Testosterone, the primary sex hormone in both men and women, plays a crucial role in the development of reproductive tissues, as well as secondary sexual characteristics like muscle and bone mass and body hair. It is essential for overall health, well-being, and the prevention of conditions such as osteoporosis. Testosterone exhibits remarkable anabolic properties, promoting muscle growth, protein synthesis, and glycogen supply to muscles. It is widely utilized in medical treatments for gender dysphoria, male hypogonadism, and specific types of breast cancer. Although testosterone is renowned in the athletic world for its muscle-building effects, it serves as a vital hormone for various physiological processes.

Mechanism of Action

Testosterone binds to androgen receptors and acts as a precursor to dihydrotestosterone (DHT), a biologically active androgen formed through the conversion of testosterone by the 5α-reduction enzyme. DHT exhibits a stronger affinity for androgen receptors. These hormone-receptor interactions initiate changes in gene expression, leading to androgenic effects. Aromatase can convert testosterone to estrogen, a process known as aromatization. Estrogens, predominantly rather than testosterone itself, regulate the hypothalamus-pituitary-testes axis and suppress endogenous testosterone production when exogenous testosterone is administered.

Medical Use

Testosterone is classified as an essential medicine by the World Health Organization, emphasizing its critical role in healthcare. It is employed in hormone replacement therapy (HRT) and testosterone replacement therapy (TRT) for conditions such as gender dysphoria, male hypogonadism, and certain breast cancers. Age-related testosterone decline necessitates HRT or TRT to maintain optimal health and quality of life. Inadequate testosterone levels in men can lead to frailty, bone loss, and other abnormalities. Furthermore, testosterone influences cognitive functions, including mood, spatial ability, attention, memory, and the risk of cognitive decline and dementia.

Testosterone for Seniors

Men over 35 who experience diminished well-being are often advised to undergo blood testosterone testing. If levels fall below 12 nmol/l, hormone replacement therapy is recommended. This approach offers several benefits, including improved body composition with increased muscle mass and decreased fat, rejuvenating effects, and enhanced sexual function. It is crucial to monitor lipid profiles, blood parameters, and hormone levels during therapy. For individuals desiring to conceive, additional therapy with gonadotropins may be necessary since testosterone therapy suppresses natural gonadotropin production.

Testosterone in Sports

Testosterone is widely favored by athletes and bodybuilders due to its ability to enhance muscle mass and strength. It exhibits both anabolic and androgenic effects, binding to androgen receptors and activating gene expression to stimulate muscle growth. Testosterone also facilitates regeneration processes, improves oxygen capacity and nitric oxide production, and positively impacts stamina and exercise performance. Typical dosages in sports range from 250-500 mg per week, with adjustments made based on individual factors such as body weight and response. Aromatase inhibitors are often used to mitigate estrogenic side effects.

Dos ages

• Beginner: 250 mg per week
• The average dosage: 300-750 mg per week
• High dosage: 750+ mg per week

Effects

• Increased muscle mass
• Development of male sexual characteristics
• Enhanced spermatogenesis and male behavior
• Fat burning
• Increase in strength
• Elevated libido
• Reduction in blood cholesterol levels
• Lower risk of heart ischemia and coronary heart disease
• Stimulation of erythropoiesis and redistribution of subcutaneous fatty tissue
• Modulation of nitrogen and phosphorus metabolism

Side Effects

• Increased blood pressure
• Elevated sexual behavior
• Hemoconcentration (blood clotting)
• Potential for blood clots in arterial and venous vessels
• Water retention (edema)
• Masculinization
• Aggression, agitation, irritability
• Alopecia (scalp baldness)
• Acne
• Insomnia (rare)

Profile

• Half-life: 7-15 days
• Frequency of injections: 4-7 days

Pharmaceutical Form

Oily solution for intramuscular injection.

Contraindications

• Pregnancy
• Known or suspected carcinoma of the prostate or breast
• Breastfeeding
• Hypersensitivity to the active substance or any of the excipients

Storage

• Do not use after the expiry date
• Store between 8ºC and 30ºC
• Avoid freezing
• Protect from light