Tyroid Mixos 10 mcg and 62.5 mcg (T3/T4)

• Active ingredient: Triiodothyronine (T3) and Thyroxine (T4)
• Type: Thyroid
• Form: Oral (pills)

Description

Thyroid hormones are biologically active substances that contain iodine. They play crucial roles in the normal development of a growing body, particularly the central nervous system, and regulate metabolism in adults, influencing nearly all organs and tissues. These hormones control energy expenditure, its speed, and volume.

The thyroid gland stores significant reserves of thyroid hormones to fulfill its functions. Metabolism of thyroid hormones primarily occurs in the liver, with partial conversion taking place in target tissues like the brain. The level of thyroid hormones in the blood is tightly regulated by the adenohypophysis using TSH (thyroid-stimulating hormone) and negative feedback mechanisms. TSH signals the production of thyroid hormones, mainly T4, which can be converted to T3 primarily in tissues.

Thyroid hormones exert their effects mainly through intracellular receptors, influencing the expression of specific genes.

Purposes of Use

Many patients on replacement therapy struggle to efficiently convert levothyroxine (T4) to triiodothyronine (T3), even though the body requires both hormones. This inefficiency may be due to liver overload with toxins or a deficiency in zinc, which is necessary for the conversion of T4 to T3. Other factors, including nutrient depletion and excess iodine, can also interfere with this conversion.

Due to the ongoing debate about whether hypothyroid patients can achieve optimal replacement with T4 alone, dissatisfaction with T4 monotherapy remains high. Numerous studies have explored the potential benefits of combined T3 and T4 therapy. Adding T3 to adequate T4 dosing to normalize serum T4 and TSH levels can increase T3 to at least the middle-normal range.

This thyroid hormone compound is prescribed for replacement therapy in cases of thyroid gland resection, radioiodine therapy, thyroid oncological conditions, or suppressive therapy.

Replacement therapy is recommended for hypothyroidism of any cause, including:

- Primary and secondary hypothyroidism

- Diffuse and mixed euthyroid goiter

- Subacute and autoimmune thyroiditis

- Thyroid cancer (following surgical treatment)

- Obesity with hypothyroidism

Dosage

The initial dosage is low, with an increase to the therapeutic dose over 3-4 weeks. In patients with cardiac pathology or over 65 years of age, thyroid hormone doses are reduced to minimize cardiovascular side effects. Children and pregnant women have increased thyroid hormone requirements. The addition of adreno-blockers can aid in adapting to thyroid hormone treatment.

How to Use

The recommended starting dosage is typically 1 pill per day, increasing by 1 pill every 5-6 days. The maximum daily dosage is 3 pills mcg. Spread the tablets throughout the day. The maximum cycle duration is seven weeks, with at least six weeks between cycles to restore normal thyroid function. It is common to stack it with clenbuterol to enhance fat-burning effects.

• Average dose: 1 to 3 pills per day
• Effective dosage: pyramidal method (1-2-3-3-2-1)
• Proven cycle: 5-6 weeks

Effects

• Boosts metabolism
• Increases heat production
• Enhances fat burning
• Stimulates the central nervous system
• Reduces the need for sleep
• Improves physical performance

Side Effects

• Tachycardia and increased blood pressure
• Agitation
• Insomnia
• Muscle tremors
• Dry mouth
• Sweating
• Feeling hot

Warnings

• Please note that using Tyrois mixos without any anabolic assistance can lead to significant muscle loss.

Profile

• Half-life: 5-7 days
• Frequency of intake: 1-2 times per day

Contraindications

• Acute myocardial infarction
• Uncorrected adrenal insufficiency
• Acute myocarditis and pancarditis
• Active cardiac arrhythmias
• Thyrotoxicosis
• Hyperthyroidism

Storage Instructions

• Keep away from children
• Store in a cool, dry place, away from direct sunlight
• Store at room temperature
• Do not use after the expiry date