CJC1295 with DAC 2mg

Description:

CJC-1295 is a peptide hormone composed of 30 amino acids. It acts as an analog of somatoliberin, a natural stimulator of growth hormone secretion. CJC-1295 targets the nucleus of the anterior pituitary gland, stimulating the release of growth hormone. The substance binds to GHRH receptors, which are part of the G-protein-coupled receptor group. The version of CJC-1295 with DAC (Drug Affinity Complex) binds to plasma proteins, such as albumin, resulting in an extended duration of action compared to the version without DAC, which lasts only 30 minutes.

GHRH Group:

GHRH stands for Growth Hormone Releasing Hormone or Somatoliberin. It is a peptide hormone consisting of 44 amino acids and is produced in the hypothalamus. GHRH stimulates the release of growth hormone from the anterior pituitary gland in a pulsatile manner, contributing to slow-wave sleep.

Mechanism of action:

Somatoliberin is released from arcuate neurons and transported to the anterior pituitary gland, where it stimulates the release of growth hormone by binding to specific receptors. It opposes the action of somatostatin, a hormone that inhibits growth hormone secretion. The pulsatile release of somatoliberin and somatostatin results in a pulsatile secretion of growth hormone. GHRH peptides work when somatostatin levels are low or its activity is minimal, typically during natural releases or after injections of growth hormone. GHRH peptides increase endogenous growth hormone levels, leading to positive effects such as fat loss, muscle gain, improved cholesterol levels, and enhanced healing.

Purpose of use:

The use of GHRH peptides, including CJC-1295, offers benefits such as increased fat loss, improved muscle gain, reduced cholesterol and triglyceride levels, and enhanced healing after injuries. These peptides do not negatively impact blood sugar levels and help establish a natural pulsatile character of growth hormone peaks in the blood.

Effects:

• Sustained increase in growth hormone and IGF-1 levels
• Reduction in visceral adipose tissue
• Lowered total cholesterol and triglyceride levels
• Increased muscle mass

Side effects:

• Short-term facial redness and pain at the injection site
• Arthralgia (joint pain)
• Myalgia (muscle pain)

Tesamorelin, GRF (1-44):

Tesamorelin is a growth hormone stimulant with a longer half-life compared to other GHRH peptides. It contains all 44 amino acids of somatoliberin and is effective for approximately 4-5 hours. It is commonly used in medical practice as a growth hormone secretion stimulator.

Sermorelin, GRF (1-29):

Sermorelin is a peptide consisting of the first 29 amino acids of somatoliberin. It has a short half-life of approximately 2 hours but can significantly increase growth hormone levels when combined with GHRP peptides.

Mod GRF (1-29):

Mod GRF (1-29 ) is similar to sermorelin but has a longer half-life of approximately 30 minutes. It is also known as modified GRF (1-29) or Mod GRF (1-29).

CJC-1295 with DAC:

CJC-1295 with DAC is derived from Mod GRF (1-29) and has an even longer half-life, lasting several days. This peptide provides an extended period of effectiveness and maintains the pulsatile nature of growth hormone release.

Application scheme:

GHRH peptides typically have short half-lives, requiring frequent injections, often 3-4 times a day. CJC-1295 DAC, with its longer duration of action, can be injected twice a week. GHRH peptides are commonly combined with GHRP peptides such as GHRP-2, GHRP-6, hexarelin, or ipamorelin for a synergistic effect.

How to prepare a solution:

To prepare a solution for injection, a diluent is added to a vial containing the lyophilized powder. Care should be taken to avoid direct injection into the powder. The vial is gently mixed until the powder is dissolved, resulting in a clear liquid ready for use. Peptides should not be mixed in the same syringe to prevent degradation.

Application:

The injection can be administered subcutaneously or intramuscularly, depending on personal preference.

Storage:

The prepared solution can be stored in a refrigerator at a temperature of 2-8°C for approximately 21 days. The storage time may increase if bacteriostatic water is used as the diluent.