Accutadyn (Isotretinoin)

• Active ingredient: Isotretinoin
• Type: A drug for the treatment of acne. Retinoid
• Form: Oral (pills)

Description

Isotretinoin is a highly effective medication for treating severe acne. It inhibits sebaceous gland functioning, reducing oil production and preventing acne development. This anti-acne medication is chemically related to retinoic acid and retinol (Vitamin A).

Mechanism of action

Isotretinoin alters the cell cycle, differentiation, survival, and apoptosis, leading to reduced sebum production, prevention of skin pore blockage, and inhibition of acne-causing bacteria growth. It also induces apoptosis in sebocytes and reduces comedone formation.

Purposes of use

Isotretinoin is utilized by bodybuilders and athletes to address acne, a common side effect of anabolic/androgenic steroid use, during steroid therapy.

Dosage

The recommended dosage of Isotretinoin ranges from 0.5 to 1 mg/kg of body weight per day. Exceptional cases may require higher dosages up to 2 mg/kg/day. The daily dose is divided into two equal doses taken at separate times of the day. It is recommended to take Isotretinoin with meals for better absorption.

Effects

• Treats acne by reducing sebum production
• Prevents clogged pores
• Decreases growth of skin bacteria
• Has anti-inflammatory effects

Side effects

Isotretinoin is a potent medication with potential side effects. It should not be used by women who may become pregnant due to serious complications for fetal development. Side effects may include hepatotoxicity, inflammatory bowel disease, pancreatitis, suppressed HDL cholesterol levels, elevated triglyceride values, visual impairment, and heart palpitations.

Warnings

Isotretinoin has been associated with an increased risk of depression, as indicated by FDA-approved literature.

During an isotretinoin cycle, it is important to avoid alcohol consumption and vitamin A supplements.

Profile

• Half-life: 7-39 hours
• Frequency of intake: 2 times a day

Contraindications

• Isotretinoin is contraindicated during pregnancy due to major risks.

How to store

• Keep away from children
• Store in a cool, dry place away from direct sunlight
• Store at room temperature
• Do not use after the expiry date