Propios 100 mg/ml (Testosterone Propionate)

• Active ingredient: Testosterone Propionate
• Type: Anabolic steroid (Testosterone derivative)
• Form: Injections

Carrier oil: Sesame oil

Description

Testosterone is a primary sex hormone in humans, playing a crucial role in the development of reproductive tissues and secondary sexual characteristics. It promotes increased muscle and bone mass, body hair growth, and overall well-being. Testosterone, classified as an anabolic steroid, exhibits significant anabolic properties, such as muscle mass increase, protein synthesis acceleration, glycogen supply enhancement, and more. It regulates numerous processes in the body, making it essential for individuals of all ages, including those on hormone replacement therapy (HRT) and athletes during steroid cycles.

Mechanism of Action

Testosterone binds to androgen receptors and serves as a precursor to dihydrotestosterone, a biologically active androgen. Dihydrotestosterone, formed through the action of the enzyme 5α-reduction on testosterone, exhibits a higher affinity for androgen receptors. The binding of testosterone or dihydrotestosterone to androgen receptors triggers cellular changes and influences gene activity. Aromatase can convert testosterone into estrogen, primarily leading to negative feedback on the hypothalamus-pituitary-testes axis, thereby suppressing endogenous testosterone secretion.

Medical Use

Testosterone is included in the World Health Organization's list of essential medicines and is used in various medical contexts. It is employed for treating gender dysphoria, male hypogonadism, and certain types of breast cancer. Additionally, testosterone replacement therapy (TRT) is utilized to maintain normal testosterone levels and counter age-related declines in health and quality of life.

Testosterone for Seniors

Men over 35 experiencing well-being issues are often advised to have their testosterone levels checked. If levels fall below 12 nmol/l, hormone replacement therapy may be recommended. This approach offers several benefits, including improved body composition with increased muscle and reduced fat, revitalized sexual function, and an overall rejuvenating effect. However, close medical supervision is necessary, monitoring lipid profiles, blood parameters, estradiol levels, and prolactin levels.

Testosterone in Sports

Testosterone is highly valued in sports due to its ability to increase muscle mass and strength. It exhibits potent anabolic effects and a strong androgenic impact. Testosterone interacts with and activates androgen receptors, leading to DNA binding and gene expression. Athletes commonly experience rapid weight gain, partially attributed to water retention and estrogenic effects. Testosterone can alleviate joint problems, enhance regenerative processes, improve oxygen capacity, and boost nitric oxide production.

Dosages

• Beginner: 50 mg every other day
• Average dosage: 100-150 mg every other day
• High dosage: 100 mg or more every day

Effects

• Increased muscle mass
• Development of male genital organs and secondary sexual characteristics
• Spermatogenesis and enhancement of male behavior
• Fat burning
• Increase in strength
• Heightened libido
• Reduction in blood cholesterol levels
• Lower risk of heart ischemia and coronary heart disease
• Stimulation of erythropoiesis and redistribution of subcutaneous fatty tissue
• Influence on nitrogen and phosphorus metabolism

Side Effects

• Increased blood pressure
• Elevated sexual behavior
• Hemoconcentration (blood clotting)
• Potential for blood clots in arterial and venous vessels
• Water retention (edema)
• Masculinization
• Aggression, agitation, irritability
• Alopecia (baldness of the scalp)
• Acne (acne)
• Insomnia (rare)

Profile

• Half-life: 20 hours
• Frequency of injections: Every 1-2 days

Pharmaceutical form

• Oily solution for intramuscular injection

Contraindications

• Pregnancy
• Known or suspected carcinoma of the prostate or breast
• Breastfeeding
• Hypersensitivity to the active substance or excipients

How to Store

• Do not use after the expiry date
• Store between 8ºC and 30ºC
• Avoid freezing
• Protect from light